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Fitzgerald CD25 ANTIBODY 10R-CD25dMS
| Synonyms | Monoclonal CD25 antibody, Anti-CD25 antibody, CD-25 antibody, CD-25, IL2Ra antibody, CD 25, CD25, CD25 IL2-R alpha TAC antibodyIL2-R alpha TAC antibody, CD 25 antibody |
|---|---|
| Specificity | Murine CD25 |
| Cross Reactivity | To be determined by end-user |
| Applications | FC, IP |
| Immunogen | CD25 antibody was raised in rat using IL-2-dependent BALB/c murine helper T-cell as the immunogen. |
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| Synonyms | Monoclonal CD25 antibody, Anti-CD25 antibody, CD-25 antibody, CD-25, IL2Ra antibody, CD 25, CD25, CD25 IL2-R alpha TAC antibodyIL2-R alpha TAC antibody, CD 25 antibody |
|---|---|
| Specificity | Murine CD25 |
| Cross Reactivity | To be determined by end-user |
| Applications | FC, IP |
| Immunogen | CD25 antibody was raised in rat using IL-2-dependent BALB/c murine helper T-cell as the immunogen. |
| Biological Significance | CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. |
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